Adrenal Function Profile Health Test

A adrenal stress hormone cortisol test.  The adrenal glands are located at the top of the kidneys and produce hormones that help the body to control blood sugar, burn protein and fat, react to stressors and regulate blood pressure. 

Results expected within: 10 working days

Adrenal Function Profile Health Test

Results are processed using our UK Laboratory partner.


What are the adrenal glands?

The adrenal glands are made up of 2 distinct components, the adrenal cortex (outer part) which produces vital hormones such as cortisol, aldosterone and DHEA and the adrenal medulla (inner part) which produces adrenaline and nor-adrenaline.

Why test adrenal function?

Optimally functioning adrenal glands are vital to the fundamental survival mechanism process of energy delivery, as they enable the body to balance energy expenditure with demand. In response to physiological or psychological stress, the adrenal glands should release appropriate levels of the necessary hormones to cope, however poor adrenal function can inhibit an individual’s ability to do so effectively. In the case of adrenal insufficiency/fatigue, it has also been shown that disruption to the HPA axis can lead to lower thyroid function, as well as inhibition of androgen synthesis including DHEA and testosterone.

If a person experiences several of the symptoms highlighted above, then this test may be extremely beneficial to help to identify whether this is due to adrenal insufficiency.

What causes adrenal insufficiency?

During acute stress, the hypothalamus stimulates the adrenal medulla to release adrenaline and nor-adrenaline, which serves to enable a fight or flight response. If the stressor is still present after this phase, a more prolonged stress response is initiated. 

Symptoms of adrenal insufficiency/fatigue?

  • Low energy
  • Craving salty foods
  • Brain fog
  • Poor sleep quality
  • Difficulty waking
  • Low libido
  • Reliance on caffeine
  • Weakened immunity
  • Inability to handle stress
  • Central weight gain

Before taking the test, it is important that the individual should:

  • Be fully hydrated
  • Avoid caffeine, alcohol or nicotine (don’t smoke during the 2 hours prior to a sample collection).
  • Avoid eating, teeth brushing/flossing or the use of mouthwash during the 2 hours prior to a sample collection
  • Have no blood from the gums within the mouth (can artificially raise readings)
  • Avoid the use of any cortisol or hydrocortisone containing medications
  • Follow the collection instructions accurately.
  • Ensure that samples are taken at the specified times


How does the test work?.

The Adrenal Function Profile uses a convenient salivary sample collection method, taken at 5 intervals throughout the day. This enables a more precise measurement of an individual’s 24-hour cyclic cortisol levels and accurately pinpoints the important cortisol surge. This test also includes a morning and afternoon DHEA measurement, to enable the identification of the hugely significant Cortisol/DHEA ratio.



A comprehensive test report will be sent that details the levels of cortisol throughout the day, as well as morning and afternoon DHEA concentration and the cortisol/DHEA ratio.

Example adrenal report



Sample requirements and results turnaround time

The test requires 5 salivary samples to be taken at specific times throughout the day. Results are available within 15 working days.

What will this test kit find out?

We can test for a range of different allergies and health markers, using one of our home-testing kits. In this kit, you'll be able to test:


Cortisol is a stress hormone produced by the adrenal glands. It is vital to survival given its role in functions such as immunity, regulating blood pressure and releasing insulin for blood sugar maintenance.

  • Cortisol

How to use this test kit



Once you've got your kit, make sure to read all of the enclosed instructions - they'll make sure you easily and safely get the best sample possible.



Take your sample using the saliva swab provided, it's super simple and super fast.



Put your sample in the prepaid envelope provided and pop it in the post. No you can sit back and relax - we'll let you know when your results are ready.

What's in this test kit?

Prepaid return envelope
Saliva swab
  • Prepaid return envelope

  • Saliva swab